Publications
Park SW, Fransson S, Sundquist F, Nilsson JN, Grybäck P, Wessman S, Strömgren J, Djos A, Fagman H, Sjögren H, Georgantzi K, Herold N, Kogner P, Granberg D, Gaze MN, Martinsson T, Karlsson K*, Stenman JJE*, Heterogeneous SSTR2 target expression and a novel KIAA1549::BRAF fusion clone in a progressive metastatic lesion following 177Lutetium-DOTATATE molecular radiotherapy in neuroblastoma: A Case Report. Front. Oncol. 14:1408729 (2024)
LeSavage B, Gilchrist AE, Krajina BA, Karlsson K, Smith AR, Karagyozova K, Klett KC, Curtis C, Kuo CJ, Heilshorn S, Engineered extracellular matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids. Nature Materials, Aug;23(8):1138-1149 (2024)
Santos AJM, Unen V, Lin Z, Ha N, Batish A, Chan JE, Choi SS, Tomaske M, Guh-Siesel A, Christophersen A, Baghdasaryan A, Yost KE, Karlsson K [and 13 others], A human autoimmune organoid model reveals IL-7 function in celiac disease. Nature 632, 401–410 (2024)
Karlsson K*, Przybilla MJ*, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, Barnes CP, Kuo CJ, Curtis C, Deterministic evolution and stringent selection during pre-neoplasia. Nature, volume 618, pages 383–393 (2023). * Equal contribution
Sockell A, Wong W, Longwell S, Vu T, Karlsson K, Mokhtari D, Schaepe J, Lo YH, Cornelius V, Kuo C, Valen DV, Curtis C, Fordyce P, A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids, Cell Systems, Volume 14, issue 9, pages 764-778(2023)
Lo YH, Kolahi K, Du Y, Chang CH, Krokhotin A, Nair A, Sobba W, Karlsson K [and 15 others], A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation. Cancer Discovery, Jun;11(6):1562-1581 (2021)
Neal JT, Li X, Zhu J., [and 31 others, including Karlsson K], Organoid Modeling of the Tumor Immune Microenvironment, Cell, Dec 13;175(7):1972-1988.e16 (2018)
Acosta J*, Joost S*, Karlsson K*, Ehrlund Anna, Li X, Auadi M, Kasper M, Arner P, Rydén M, Laurencikiene J, Single cell transcriptomics suggest that human adipocyte progenitor cells constitute a homogeneous cell population. Stem Cell Research and Therapy, Nov 7;8(1):250 (2017). * Equal contribution
Karlsson K, Lönnerberg P, Linnarsson S, Alternative TSSs are co‐regulated in single cells in the mouse brain. Molecular Systems Biology, May 11;13(5):930 (2017)
Karlsson K, Linnarsson S, Single-cell mRNA isoform diversity in the mouse brain. BMC Genomics, Feb 3;18(1):126 (2017)
Qu Y, Siggens L, Cordeddu L, Gaidzik VI, Karlsson K, Bullinger L, Döhner K, Ekwall K, Lehmann S, Lennartsson A, Cancer specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia. Blood, Feb 16;129(7):e13-e25. (2016)
Karlsson K, Sahlin E, Iwarsson E, Westgren M, Nordenskjold M, Linnarsson S, Amplification-free sequencing of cell-free DNA for prenatal non-invasive diagnosis of chromosomal aberrations. Genomics, Mar;105(3):150-8 (2015)
Kivioja T, Vaharautio A, Karlsson K, Bonke M, Enge M, Linnarsson S, Taipale J, Counting absolute numbers of molecules using unique molecular identifiers. Nature methods, Nov 20;9(1):72-4. (2011)